726. APX001 (Fosmanogepix) Is Effective in an Immunosuppressed Mouse Model of Rhizopus oryzae Infection

Leukopenia with Granulocytopenia in Experimental Mucormycosis (rhizopus Oryzae Infection

Mucormycosis was produced in rabbits with sustained, severe leukopenia and granulocytopenia induced by repeated injections of nitrogen mustard. Initially, these animals developed extensive fungus lesions at the site of inoculation which later became granulomatous and tended to heal. Only the early phases of host resistance appeared impaired by the virtual elimination of the polymorphonuclear le...

APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection

Subcutaneous mucormycosis caused by Rhizopus oryzae probable nosocomial acquired infection.

The Authors present a case of subcutaneous mucormycosis occurring in a patient with clinical and biochemical evidence of diabetic ketoacidosis. The clinical, mycological and histopathological features are described, emphasizing the relevance of a rapid diagnosis in order to stablish early treatment. The clinical forms of mucormycosis and the main associated conditions are briefly reviewed as we...

An unusual case of nasal mucormycosis caused by Rhizopus oryzae in a German shepherd dog

This study represents an unusual case of mucormycosis localized in nasal cavity of a German shepherd dog. The patient was a 1-year-old male guard dog with unilateral nasal epistaxis, mucopurulent nasal discharge, sneezing and nose pawing. The dog had a history of head trauma about 2 months before admission, which was associated with mild self-limited epistaxis. Initial nasal rhinoscopy showed s...

cost benefits of rehabilitation after acute coronary syndrome in iran; using an epidemiological model

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